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Naproxen is also effective in treating other mild to moderate pain, including menstrual pain, headache, toothache, and temporarily reduces fever.

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The drugs were blinded, which means the patients did not know which medication they were taking, or if they were taking a placebo.

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The 200-mg strength of ibuprofen and the 220-mg strength of naproxen are available without a prescription.

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Today, studies can run for years.